After Treatment for Vaginal Cancer
For some people with vaginal cancer, treatment can remove or destroy the cancer. You might be relieved to finish treatment but find it hard not to worry about cancer coming back.
For other people, the cancer might never go away completely. They might get regular treatments to help keep the cancer in check. Learning to live with cancer that does not go away can be difficult, but many people find ways to manage their health and maintain a good quality of life.
Follow-up care
During and after treatment, it¡¯s very important to go to all your follow-up appointments. During these visits, your cancer care team will watch for signs of vaginal cancer coming back (recurrence), as well as any side effects of the treatment you¡¯ve had.
What¡¯s a survivorship care plan?
Talk with your care team about developing a survivorship care plan for you. This plan can guide your next steps after treatment, including follow-up appointments and ways to stay healthy.
A survivorship plan might include:
- A summary of the diagnosis, tests done, and treatments given
- A suggested schedule for follow-up exams and tests
- A schedule for other tests you might need in the future, such as tests to look for long-term health effects from your cancer or its treatment
- A list of possible late or long-term side effects from your treatment, including what to watch for and when you should contact your healthcare team
- Diet and physical activity suggestions
- Reminders to see your primary care provider (PCP) for routine healthcare and cancer screening
What to expect
When treatment ends, your doctors will still want to watch you closely. Follow-up visits often include careful physical exams, which could include pelvic exams, Pap tests, colposcopy, blood tests, or imaging tests. How often you follow up with your care team will depend on your cancer, its response to treatment, and other factors.
Almost any cancer treatment can have side effects. Some might last only a short time, but others can last longer or might not show up until months or years later. It¡¯s important to report any new symptoms to your cancer care team right away, so that they can find a cause and treat it if needed.
Questions to ask your care team
- Do I need a special diet after treatment?
- Are there any limits on what I can do?
- What symptoms should I watch for?
- What kind of exercise should I do now?
- What type of follow-up will I need after treatment?
- How often will I need to have follow-up exams and imaging tests?
- Will I need any blood tests?
- How will we know if the cancer has come back? What should I watch for?
- What will my options be if the cancer comes back?
Staying prepared and organized
Even after treatment, it¡¯s very important to stay organized and on top of your health. Keeping your records and health insurance coverage in order makes it easier to manage your follow-up care, future checkups, and any new concerns that might come up.
Keep your health insurance
It¡¯s very important to keep health insurance. Insurance can help cover the cost of follow-up visits, tests, and any care you might need in the future. No one wants to think about their cancer coming back, but it¡¯s best to be prepared.
Save your medical records
At some point after your treatment, you might see a new doctor who doesn¡¯t know your cancer history. Keep copies of your medical records so you can easily share the details of your diagnosis and treatment when needed.
Late and long-term effects of treatment
People who are treated for vaginal cancer can be at risk for several health problems after treatment.
Long-term side effects can last for months or years after treatment. Late effects can take months or years to develop after treatment.
It¡¯s important to ask your care team what health problems you might have, so you know what to watch for. The earlier problems are recognized, the more likely they can be treated. Your risk will depend on a few factors, including the types and doses of treatments you received.
Adopting healthy behaviors such as not smoking, eating well, getting regular physical activity, and staying at a healthy weight might help prevent long-term health problems.
Treatments for vaginal cancer, such as brachytherapy, surgery, and radiation, can leave vaginal tissue fragile. After treatment, the vagina might be scarred, shortened or tight. Your vagina might be reconstructed from other tissues and might need extra care. Pelvic floor or vaginal therapy might help you recover after treatment.
Some people might be advised to use vaginal dilators, which are put into the vagina to gently stretch the vaginal tissue, gradually making it more elastic over time.
Some treatments can also cause vaginal dryness, making sex uncomfortable. The use of lubrication or other topical medicines can help.
Learn more in Treating Sexual Problems for Women With Cancer.
Some people must have their uterus removed as a part of their treatment. Others might get radiation to the pelvis. These treatments can affect fertility. Treatments that affect the ovaries¡¯ ability to make hormones might also cause early menopause in younger people.
Common symptoms of early menopause include fatigue, hot flashes, night sweats, vaginal dryness, reduced sexual desire and pleasure, bone loss, and changes in mood.
Talk with your care team about fertility preservation options before treatment and ways to treat symptoms of early menopause.
Radiation scarring can cause problems like narrowing of the bowel or irritation of the bladder (cystitis) or rectum (proctitis). This can cause symptoms such as frequent or painful urination, or constipation. This can begin months or years after treatment.
Radiation can also cause abnormal connections (called fistulas) to form between the vagina and the bladder, rectum, or uterus.
Pelvic radiation can weaken the bones, leading to fractures of the hips or pelvic bones. Low estrogen levels after radiation to the ovaries can also increase the risk of fractures.
Cancer treatments are an important part of treating cancer, but some treatments can increase the risk of developing another cancer later in life. Survivors of vaginal cancer who were treated with certain chemotherapy medicines (platinum chemotherapy such as cisplatin or carboplatin) or radiation have a higher risk of a second cancer later on.
Adopting healthy behaviors such as not smoking, eating well, getting regular physical activity, and staying at a healthy weight might help prevent long-term health problems.
If lymph nodes are removed as a part of surgery to treat vaginal cancer, it can affect fluid drainage from the legs. If fluid builds up, it can cause lymphedema (swelling). This is more common if radiation or chemotherapy is given after surgery.
Support stockings or special compression devices might help reduce swelling. People with lymphedema need to be very careful to avoid an injury or infection in the affected leg or legs.
Learn more in Lymphedema.
People treated with platinum chemotherapy, such as cisplatin, are at increased risk of developing hearing problems.
During and after treatment, you might have a test called an audiogram to assess any damage from chemo. If your hearing has been affected by chemotherapy, your cancer team might recommend seeing a hearing specialist, called an audiologist, to discuss hearing aids.
Your kidneys can be affected by:
- Chemo drugs like cisplatin
- Radiation to the abdomen
Your cancer care team might recommend regular kidney function testing to find and manage any problems after treatment.
is damage to the nerves that control how the body moves and feels. It might occur after treatment with drugs like cisplatin. Symptoms of neuropathy, like numbness, pain, or tingling, might get better once treatment is stopped, but sometimes they can be permanent.
If the cancer comes back
If the cancer does come back or recur at some point, your treatment options will depend on where the cancer is, what treatments you¡¯ve had before, and your health. For more information on how recurrent cancer is treated, see Treatment Options for Vaginal Cancer, by Stage and Type.
For more general information on recurrence, you might also want to see Understanding Recurrence.
Social and emotional health after cancer
Some amount of feeling depressed, anxious, or worried is normal when cancer is a part of your life. Changes in hormones or sexual function after cancer treatment can make these feelings more intense.
Some feelings might last a long time and can include:
- Dealing with physical changes that happen because of treatment
- Worrying about the cancer returning or new health problems developing
- Being treated differently or discriminated against by friends, partners, coworkers, employers, and others
You might also feel:
- Resentful for having had cancer
- Resentful for going through treatment when others didn¡¯t have to
- Guilty for surviving cancer when other friends with cancer did not
Learn more in Life after Cancer.
If your feelings are getting in the way of your daily life, consider reaching out for support. The ÌÇÐÄTV¹ÙÍø Cancer Society is here to help. The National Cancer Information Center is available 24/7 at 1-800-227-2345 to discuss support resources in your community.
- Written by
- References
Developed by the ÌÇÐÄTV¹ÙÍø Cancer Society medical and editorial content team with medical review and contribution by the ÌÇÐÄTV¹ÙÍø Society of Clinical Oncology (ASCO).
Charatsi D, Vanakara P, Evaggelopoulou E, et al. Vaginal dilator use to promote sexual wellbeing after radiotherapy in gynecological cancer survivors. Medicine (Baltimore). 2022;101(4):e28705.
National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Vaginal Cancer Version 2.2026 ¨C December 4, 2025. Accessed at https://www.nccn.org/professionals/physician_gls/pdf/vaginal.pdf on September 8, 2026.
Okpo E, Othieno R, Eleje GU, Oragwu CI, Eke AC. Interventions to improve psychosexual function in women treated for gynaecological cancers. Cochrane Database of Systematic Reviews 2022, Issue 8. Art. No.: CD014674.
Rock CL, Thomson C, Gansler T, et al. ÌÇÐÄTV¹ÙÍø Cancer Society guideline for diet and physical activity for cancer prevention. CA Cancer J Clin. 2020;70(4):245-271.
Last Revised: October 23, 2026
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